--- title: "From Image to Results: A Year in Review" description: "In the series \"From Image to Results\", explore various case studies explaining how to reach results from your demanding samples and acquire images in an efficient way. For each case study, arivis together with ZEISS Microscopy highlighted different samples, imaging systems, and research questions." image: https://www.arivis.com/hubfs/from-image-to-results-banner-blog-zeiss-arivis.jpeg --- arivis Scientific Image Analysis - [Contact](https://www.arivis.com/contact) Close - Products - ZEISS arivis Pro - [ZEISS arivis Pro](https://www.arivis.com/products/pro) - [ZEISS arivis Pro VR](https://www.arivis.com/products/pro/vr) - [ZEISS arivis Hub](https://www.arivis.com/products/hub) - [ZEISS arivis Cloud](https://www.arivis.com/products/cloud-ai) - Resources - [Publications](https://www.arivis.com/resources/publications) - [Case Studies](https://www.arivis.com/resources) - [Mitochondria Analysis with Deep Learning](https://www.arivis.com/case-study/deep-learning-segmentation-mitochondria) - [Compartmentalization of Chromatin](https://www.arivis.com/case-study/distribution-and-compartmentalization-chromatin-nucleus) - [Gastrulation & Migration Phenotypes](https://www.arivis.com/case-stydy/gastrulation-and-migration-phenotypes) - [Advanced 4D Tracking of Meiotic Spindle Dynamic](https://www.arivis.com/case-study/advanced-4d-tracking-of-meiotic-spindle-dynamic) - [Migration of Interneurons in Developing Mouse Brain](https://www.arivis.com/case-study/migration-of-interneurons-in-the-developing-mouse-brain) - [Exploring Whole Organisms at Single-cell Resolution](https://www.arivis.com/case-study/exploring-whole-organisms-at-single-cell-resolution) - [Image Analysis Workflow for EM images](https://www.arivis.com/use-case/image-analysis-workflow-for-mining-em-images) - [Webinars and Workshops](https://www.arivis.com/resources/webinars-workshops-trainings) - [Tutorials](https://www.arivis.com/tutorials-series) - [AI eBook](https://www.arivis.com/ai-ebook) - [AI Blog](https://www.arivis.com/blog) - How to's - [AI, ML and DL](https://www.arivis.com/applications/ai-machine-learning-deep-learning) - [Importing from Open Source](https://www.arivis.com/applications/exchange-objects-open-source-software) - [Region Growing](https://www.arivis.com/applications/region-growing) - [Membrane-based Segmentation](https://www.arivis.com/use-case/membrane-based-segmentation) - [Colocalization](https://www.arivis.com/use-case/colocalization) - [Customizable Magic Wand](https://www.arivis.com/use-case/customizable-magic-wand) - [Color Settings](https://www.arivis.com/use-case/use-case-color-settings) - [Tracking](https://www.arivis.com/applications/dynamics-and-tracking) - [Blob Finder](https://www.arivis.com/use-case/blob-finder) - [Visualization in Charts and 4D viewer](https://www.arivis.com/use-case/use-case-visualization-in-charts-and-4d-viewer) - Service & Support - [Knowledge Base](https://kb.arivis.com/) - [Software Newsletter](https://www.arivis.com/contact/newsletter) - [About](https://www.arivis.com/about-us) - [News](https://www.arivis.com/arivis-news) - [Career](https://www.arivis.com/career) - [Partners](https://www.arivis.com/technology-partner) - [Awards](https://www.arivis.com/awards) SEARCH [![Contact](https://hubspot-no-cache-eu1-prod.s3.amazonaws.com/cta/default/9058989/f6b72482-6e31-424f-9f83-11d8125b109d.png)](https://hubspot-cta-redirect-eu1-prod.s3.amazonaws.com/cta/redirect/9058989/f6b72482-6e31-424f-9f83-11d8125b109d) [![partner-logo-zeiss-1](https://www.arivis.com/hs-fs/hubfs/arivis-website-assets/images/partner/partner-logo-zeiss-1.png?width=48&height=48&name=partner-logo-zeiss-1.png)](https://www.arivis.com) [![partner-logo-zeiss-1](https://www.arivis.com/hs-fs/hubfs/arivis-website-assets/images/partner/partner-logo-zeiss-1.png?width=40&height=40&name=partner-logo-zeiss-1.png)](https://www.arivis.com) - Products - ZEISS arivis Pro - [ZEISS arivis Pro](https://www.arivis.com/products/pro) - [ZEISS arivis Pro VR](https://www.arivis.com/products/pro/vr) - [ZEISS arivis Hub](https://www.arivis.com/products/hub) - [ZEISS arivis Cloud](https://www.arivis.com/products/cloud-ai) - Resources - [Publications](https://www.arivis.com/resources/publications) - [Case Studies](https://www.arivis.com/resources) - [Mitochondria Analysis with Deep Learning](https://www.arivis.com/case-study/deep-learning-segmentation-mitochondria) - [Compartmentalization of Chromatin](https://www.arivis.com/case-study/distribution-and-compartmentalization-chromatin-nucleus) - [Gastrulation & Migration Phenotypes](https://www.arivis.com/case-stydy/gastrulation-and-migration-phenotypes) - [Advanced 4D Tracking of Meiotic Spindle Dynamic](https://www.arivis.com/case-study/advanced-4d-tracking-of-meiotic-spindle-dynamic) - [Migration of Interneurons in Developing Mouse Brain](https://www.arivis.com/case-study/migration-of-interneurons-in-the-developing-mouse-brain) - [Exploring Whole Organisms at Single-cell Resolution](https://www.arivis.com/case-study/exploring-whole-organisms-at-single-cell-resolution) - [Image Analysis Workflow for EM images](https://www.arivis.com/use-case/image-analysis-workflow-for-mining-em-images) - [Webinars and Workshops](https://www.arivis.com/resources/webinars-workshops-trainings) - [Tutorials](https://www.arivis.com/tutorials-series) - [AI eBook](https://www.arivis.com/ai-ebook) - [AI Blog](https://www.arivis.com/blog) - How to's - [AI, ML and DL](https://www.arivis.com/applications/ai-machine-learning-deep-learning) - [Importing from Open Source](https://www.arivis.com/applications/exchange-objects-open-source-software) - [Region Growing](https://www.arivis.com/applications/region-growing) - [Membrane-based Segmentation](https://www.arivis.com/use-case/membrane-based-segmentation) - [Colocalization](https://www.arivis.com/use-case/colocalization) - [Customizable Magic Wand](https://www.arivis.com/use-case/customizable-magic-wand) - [Color Settings](https://www.arivis.com/use-case/use-case-color-settings) - [Tracking](https://www.arivis.com/applications/dynamics-and-tracking) - [Blob Finder](https://www.arivis.com/use-case/blob-finder) - [Visualization in Charts and 4D viewer](https://www.arivis.com/use-case/use-case-visualization-in-charts-and-4d-viewer) - Service & Support - [Knowledge Base](https://kb.arivis.com/) - [Software Newsletter](https://www.arivis.com/contact/newsletter) - [About](https://www.arivis.com/about-us) - [News](https://www.arivis.com/arivis-news) - [Career](https://www.arivis.com/career) - [Partners](https://www.arivis.com/technology-partner) - [Awards](https://www.arivis.com/awards) [![Contact](https://hubspot-no-cache-eu1-prod.s3.amazonaws.com/cta/default/9058989/f6b72482-6e31-424f-9f83-11d8125b109d.png)](https://hubspot-cta-redirect-eu1-prod.s3.amazonaws.com/cta/redirect/9058989/f6b72482-6e31-424f-9f83-11d8125b109d) Dec 14, 2021, 12:45:44 PM 9 min read # From Image to Results: A Year in Review [Previous Post](https://www.arivis.com/arivis-news/neuroscience-conference-2021) [Next Post](https://www.arivis.com/arivis-news/arivisvision4d36) In the joint series "From Image to Results", explore various case studies explaining how to reach results from your demanding samples and acquire images in an efficient way. For each case study, arivis together with ZEISS Microscopy highlighted different samples, imaging systems, and research questions. In this blog article we will present the highlights of 2021 that will inspire your own research in scientific imaging. ![fromimagetoresults-vesicletrafficking-small](https://www.arivis.com/hs-fs/hubfs/fromimagetoresults-vesicletrafficking-small.jpeg?width=700&height=400&name=fromimagetoresults-vesicletrafficking-small.jpeg) Sample: Cos7 cells transiently transfected with mEmerald-Rab5a and Golgi7-tdTomato, Task: Track both types of vesicles, volume & distances over time, colocalization​, Results: Graphic visualization of tracks and cells in a movie and resulting data as time line along track, scatter plots, System: [ZEISS Lattice Lightsheet 7](https://www.zeiss.com/microscopy/int/products/imaging-systems/lattice-lightsheet-7.html), Software: [arivis Vision4D](https://www.arivis.com/solutions/vision4d).  Vesicle Trafficking in cos7 Cells: We start the series with an analysis of vesicle trafficking in Cos7 cells. The goal is to generate a high-resolution longitudinal study of vesicle trafficking within a single cell to explore some basic observations concerning vesicle transport. We then showcase image analysis tools to segment vesicles and generate vesicle tracks to derive meaningful data to confirm our observations. [Vesicle Trafficking with Vision4D](https://www.zeiss.com/microscopy/int/cmp/lsc/21/from-image-to-results/vesicle-trafficking.html)   ![fromimagetoresults-genotoxicity-small](https://www.arivis.com/hs-fs/hubfs/fromimagetoresults-genotoxicity-small.jpeg?width=795&name=fromimagetoresults-genotoxicity-small.jpeg)Sample: Clear-cell renal carcinoma cell line SLR22, Task: DNA-damage analysis, Results: Cell-cycle specific DNA-damage elucidates drug mechanism, System: [ZEISS Axio Observer](https://www.zeiss.com/microscopy/int/products/light-microscopes/axio-observer-for-biology.html), Software: [arivis Vision4D](https://www.arivis.com/solutions/vision4d), [arivis VisionHub.](https://www.arivis.com/visionhub) High Content Imaging for Genotoxicity: In this second episode, we set up an application example to perform DNA-damage analysis by employing ZEISS Axio Observer and the arivis Vision4D image analysis software. We highlight the general analysis as performed with one drug. The aim is to show how to automate imaging and analysis procedures, to the point that the whole process can be scaled easily to perform high-content screening (HCS) or be adapted to other complex experimental settings. ![high-content-imaging-genotoxicity-vision4d](https://www.arivis.com/hs-fs/hubfs/high-content-imaging-genotoxicity-vision4d.png?width=3868&name=high-content-imaging-genotoxicity-vision4d.png)     [High Content Imaging WITH VISION4D](https://www.zeiss.com/microscopy/int/cmp/lsc/21/from-image-to-results/high-content-imaging-for-genotoxicity.html)   ![fromimagetoresults-organoidanalysis-small](https://www.arivis.com/hs-fs/hubfs/fromimagetoresults-organoidanalysis-small.jpeg?width=795&name=fromimagetoresults-organoidanalysis-small.jpeg)Sample: Intestinal organoids, Task: Study the role of Wnt signaling in organoid formation, Results: Analysis of an organoid experiment, System: [ZEISS Celldiscoverer 7](https://www.zeiss.com/microscopy/int/products/imaging-systems/celldiscoverer-7-automated-microscope-for-live-cell-imaging.html), Software: [arivis Vision4D](https://www.arivis.com/solutions/vision4d), [arivis VisionHub](https://www.arivis.com/visionhub). Organoid Analysis: In this third episode, we showcase a simple imaging experiment performed on intestinal organoids treated with and without a Wnt-inhibiting drug, with the experimental goal to study the role of Wnt signaling in organoid formation.​ Once a pipeline has been created and optimized in arivis Vision4D by testing on a sample set of images, it is then possible to scale up the analysis by use of the server-based VisionHub platform. As arivis VisionHub is accessed over the web, users can easily upload pipelines to their datasets, run batch analysis and then have the results readily available within the web-based user interface.​ [ORGANOID ANALYSIS WITH VISION4D](https://www.zeiss.com/microscopy/int/cmp/lsc/21/from-image-to-results/organoid-analysis.html)   We hope that you find these case studies interesting and inspiring in your own research. If you'd like to talk about any of these studies with an arivis expert we invite you to request a personal remote demo. Of course you can also register for your personal free trial version of Vision4D and see for yourself what our scientific imaging platform can do with your scientific datasets - we support a vast selection of file formats and systems. We will continue with this exciting series in 2022 - see you next year!  [REQUEST A PERSONAL REMOTE DEMO](https://www.arivis.com/talk-with-an-expert-form) [GET YOUR FREE TRIAL VERSION TODAY](https://register.arivis.com/) ## RELATED ARTICLES ## [arivis Marketing Mar 26, 2023, 6:35:20 PM 10 min read arivis Vision4D 4.1 AI-assisted image analysis for everybody, anywhere: Perform local annotation and training with the new arivis AI toolkit or use ... Start Reading](https://www.arivis.com/arivis-news/arivisvision4d41) ## [arivis Marketing Jan 31, 2023, 6:53:17 PM 11 min read arivis VisionVR 4.0 Get a new perspective with VisionVR 4.0 Use your hands to move, rotate, scale and shape your digital image data. An immersive ... Start Reading](https://www.arivis.com/arivis-news/arivisvisionvr40) ## [arivis Marketing Apr 9, 2021, 11:28:21 AM 5 min read arivis VisionVR 3.4 arivis is excited to announce the latest release of its industry-leading Virtual Reality solution for interactive exploration ... Start Reading](https://www.arivis.com/arivis-news/arivisvisionvr34) **Related ZEISS Websites** [Research Microscopy](https://www.zeiss.com/microscopy/en/home.html) [ZEISS Group](https://www.zeiss.com/int) - [Privacy](https://www.zeiss.com/data-protection) - [Imprint](https://www.arivis.com/imprint) - [Contact](https://www.arivis.com/contact) Subscribe to our newsletter © Carl Zeiss Microscopy GmbH - All rights reserved - [Privacy Notice](https://zeiss.com/data-protection) - [Legal Notice](https://www.zeiss.com/microscopy/en/legal-information/legal-notice.html) - [Imprint](https://www.arivis.com/imprint) - [Contact](https://www.arivis.com/contact) - [Cookie Policy](https://www.zeiss.com/data-protection/int/cookie-policy.html) ```json { "@context" : "https://schema.org", "@type" : "BlogPosting", "author" : { "@type" : "Person", "name" : "arivis Marketing", "url" : "https://www.arivis.com/arivis-news/author/arivis-marketing" }, "dateModified" : "2023-03-29T16:23:05.974Z", "datePublished" : "2021-12-14T11:45:44.000Z", "headline" : "From Image to Results: A Year in Review", "image" : [ "https://www.arivis.com/hubfs/from-image-to-results-banner-blog-zeiss-arivis.jpeg" ], "mainEntityOfPage" : { "@id" : "https://www.arivis.com/arivis-news/from-image-to-results-2021", "@type" : "WebPage" }, "publisher" : { "@type" : "Organization", "logo" : { "@type" : "ImageObject" }, "name" : "Carl Zeiss Microscopy GmbH" } } ``` ```json { "@context" : "https://schema.org", "@type" : "VideoObject", "contentUrl" : "https://9058989.fs1.hubspotusercontent-eu1.net/hubfs/9058989/vesicle-trafficking-vision4d-clip.mp4", "dateModified" : "2022-06-01T19:47:19.097Z", "description" : "3D movie with visualized vesicle tracks; note the nuclear sphere in the side view.", "duration" : "PT10S", "height" : 480, "name" : "From Image to Results: Vesicle Trafficking", "thumbnailUrl" : "https://www.arivis.com/hubfs/vesicle-trafficking-vision4d-clip.mp4/medium.jpg", "uploadDate" : "2021-12-14T10:34:37.506Z", "width" : 640 } ``` ```json { "@context" : "https://schema.org", "@type" : "VideoObject", "contentUrl" : "https://9058989.fs1.hubspotusercontent-eu1.net/hubfs/9058989/organoid-analysis-vision4d-clip.mp4", "dateModified" : "2022-06-01T19:47:33.068Z", "description" : "", "duration" : "PT18S", "height" : 720, "name" : "Organoid Analysis with Vision4D", "thumbnailUrl" : "https://www.arivis.com/hubfs/organoid-analysis-vision4d-clip.mp4/medium.jpg", "uploadDate" : "2021-12-14T11:13:46.120Z", "width" : 1280 } ```