DRUG DISCOVERY

HIGH CONTENT SCREENING

Research Processes

Scaling up innovation

High content screening (HCS) has played a significant role in infectious disease research and drug discovery to date and can be a strong tool in the age of COVID-19 and beyond. With a focus on viral diseases, HCS has been used by laboratories around the world to help with three key interventional strategies: drug re-purposing to fast track a previously-approved drug to treat new diseases; development of new therapeutics; and vaccine development.

High-content screening for complex biology

in contrast to the luxury of screening against a critical single target protein, many of the complex diseases that we screen drugs against require a broader view of cell or tissue phenotype. This has led to a significant shift towards high-content screening. There are clearly important applications involving high-content screening that require sophisticated data analysis methods. It is encouraging to see emerging research aimed at developing suitable approaches. Perhaps most exciting is the prospect that large data sets from past publications have typically been safely archived and might be reanalyzed with some of these new methods to generate new discoveries.

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CONTACT US

For further information please contact us, we look forward to hearing from you.

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arivis-Vision4D

teaser-Vision4D

Modular software toolkit for extracting results from scientific images. Adjusts to hardware for maximum power and smooth interactivity on image datasets of unlimited size. Brings diverse tools into one environment and enables users to connect them into productive workflows. Highly interactive for optimization and quality at every step. Extendible directly via Python and connectable to other applications via libraries.

Tile Stitching
Data Transformation
Image Preprocessing & Enhancement
Segmentation
4D Tracking & Lineage
Batch application of Analysis Pipelines
Custom Computed Features of Objects
Exploration of Results overlaid on raw data
Interactive rendering of volumes and time-series
Cinematic high-resolution rendering

arivis-VisionVR

teaser-VisionVR

Display real image data in Virtual Reality by utilizing patent pending direct volume rendering techniques with no need to convert data or make surface models. Directly use your hands to move, rotate, scale, and shape your digital image data. Interactively proofread, edit, track or segment multi-dimensional images from nearly any source instrument.

 

Smooth Rendering and Visualization
Collaboration via different VR Scenarios
Direct Volume Rendering
Export Snapshots, Movies and 360°
Seamless Exchange with Desktop Application
Sculpting Tools to Add, Delete and Proof-read
Magic Wand Tools

arivis-VisionHub

teaser-VisionHub

A nucleus of computational activity and collaboration at scale. VisionHub enables design and execution of large-scale experiments that produce results from images, whether datasets are already stored or are actively being produced. Mass quantities of Imagery are onboarded and processed by a virtual team of computational workers. Smartly utilize processing cores in servers or workstations with the maximum speeds possible.

Register and browse image and data
Manage access for users and groups
Import and archive datasets into the arivis framework
Create experiments that produce results at scale
Leverage computational resources onsite and offsite
Scalable pricing model to support bursts of throughput
Visualize massive image volumes via remote rendering servers
Implement quality checks for increased efficiency and validity
Smart optimization of parallelization

RESOURCES

INDUSTRIES

Biotech

Modern usage of 3D cell and tissue culture technology are these days used more frequently to work with  living organism. 3D cell cultures today already are used instead of using expensive animal models. To view and analyse these complex structures Arvis has been developing over the last decade tools to help scientists to act faster and more accurate.

Pharma

Today discover, develop and produce drugs are becoming time critical for the success of a whole industry sector. Arivis and it’s TEAM is helping to shorten the evaluation of a new drug by delivering professional, scalable software solution to analyse and view complex imaging datasets

CRO

Contract research organisation provide to Pharmaceutical, biotechnology and medical device industry their outsourced services. To share efficient imaging results with their industry partner CRO often need to collaborate with their partner. Arivis 3D viewing and analysis software helps researchers to be more efficient in research process and collaborate their complex imaging results faster

CMO

Contract manufacturing organization needs professional and scalable imaging analysis solution in order to guaranty the quality level for Pharmaceutical industry will need today. To obtain this quality Arivis AG has developed imaging analysis tools to fulfil this high demand in imaging and Industry standards in QC/QA.