Colocalization

Colocalization Analysis

arivis Vision4D: Colocaliaztion
In fluorescence microscopy, colocalization refers to observation of the spatial overlap between two (or more) different fluorescent labels, each having a separate emission wavelength, to see if the different "targets" are located in the same area of the cell or very near to one another.
The definition can be split into two different phenomena, co-occurrence, which refers to the presence of two (possibly unrelated) fluorophores in the same voxel, and correlation, a much more significant statistical relationship between the fluorophores indicative of a biological interaction.

 

Enables you to analyze the colocalization of voxel intensities in different channels of your image data and provides interactive visualization in the 2D Viewer.

 

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